1 Post-Doc position in Molecular Biology Droplet-based microfluidics / barcoded DNA / antibody discovery

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Biochemistry Laboratory
ESPCI Paris
Prof. Andrew Griffiths

ESPCI Paris

ESPCI Paris is a major institution of higher education (a French "Grande École d’ingénieurs"), an internationally renowned research center (6 Nobel Prizes), and a fertile ground of innovation for industry (3 start-ups created/year). ESPCI is a highly multidisciplinary environment with teaching and research in physics, chemistry and biology.

Prof. Andrew Griffiths’ Lab

The research activities of the Laboratory of Biochemistry at ESPCI Paris, directed by Prof. Andrew GRIFFITHS, are based around droplet-based microfluidics, a powerful new ultrahigh-throughput system in which reaction volumes can be miniaturized by up to a million-fold compared to conventional assays in microtitre plates. This opens up exciting prospects for the development of extremely innovative systems with many applications in the Life Sciences. The successful candidates will join a highly multidisciplinary team, with experience spanning biology, chemistry and physics.

Project

Over the last decade, antibody-based therapies have made significant impacts on several diseases. Increasing efforts are being made by researchers and big pharma to find novel high-impact antibodies.
The post-doc will work on the characterization of millions of individual antibody secreting cells using a droplet-based microfluidic platform combined with DNA barcode and next generation sequencing. The project is in collaboration with the company HiFiBiO, a spin off from ESPCI, Harvard University and the Broad Institute.

Requirements

We are seeking a highly motivated Post-Doc with strong experience in molecular biology or related field. The Post-Doc should be interested in learning how to use microfluidic systems.

Flexibility, autonomy, the ability to work in a highly multidisciplinary team and good interpersonal skills are essential.

Recruitment terms :

Starting date : January 2019
Duration : 1 year renewable
Salary : according to professional experience

Address your applications (CV + cover letter) by email to :
Prof. Andrew GRIFFITHS
ESPCI Paris - Laboratory of Biochemistry
10 Rue Vauquelin
75005 Paris job-lbc@espci.fr





ÉCOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
10 Rue Vauquelin, 75005 Paris